参麦注射液对改善急性创伤患者应激反应临床探究.doc

参麦注射液对改善急性创伤患者应激反应临床探究[摘要] 目的 探讨参麦注射液改善急性创伤患者应激反应的临床效果。方法60例急性创伤患者随机分为实验组和对照组，两组均给予常规治疗，实验组加用参麦注射液。另选择30例健康人作为空白组。检测伤后4h 、24h 、30d后Cor浓度和β-end浓度（空白组仅在30d后检测1次），30d后三组均进行Scl-90心理状态评分。结果 ①实验组和对照组与空白组比较，Cor和β-end在伤后4h及24h内非常显著性升高（P＜0.01），实验组与对照组比较，对照组24h升高程度更为显著（P＜0.01）；伤后30d实验组Scl-90与空白组无显著性差异（P＞0.05），对照组SCL-90显著高于空白组和实验组 （P＜0.05）。②Scl-90总分与24h Cor浓度及24h β-end浓度均存在显著正相关（r=0.166，P＜0.05；r=0.176， P＜0.05）。结论 参麦注射液辅助治疗急性创伤患者，可以显著改善患者心理状态，而且参麦注射液本身也有一定的治疗作用，值得临床应用推广。 [关键词]参麦注射液；急性创伤； Cor；β-end；应激反应 [中图分类号]R641 [文献标识码] B [文章编号]1673-9701（2011）20-35-02 The Stress Reaction of Shenmai Injection for improving of Patients withAcuteInjury：A ClinicalStudy XIAN jianpingLI Xiangdong ZHOU YinTIAN ZongliangQIU Xiaohong Guangzhou Municipal Tianhe District Traditional Chinese Medical Hospital，Guangzhou510655， China [Abstract] Objective To explore the clinical effect of Shenmai injection for improving the stress reaction of patients with acute injuryMethods Sixty cases of patients with acute injury as studied object were randomly divided into experimental group and control group 30 cases in each.Both groups were given routine therapy， and experimental group were added with Shenmai injection30 cases of healthy peoples were as blank group. Cor and β-end were detected at 4h、24h and 30d after injury（blank group were detected only one time after 30d）， Scl-90 of three groups were detected after 30d. Results ①Experimental group and control group compared with blank group，Cor and β-end at 4h and 24h increased significantly （P＜0.01）； experimental group compared with control group， the indexes at 24h had more significantly increasing（P＜0.01）； Scl-90 between experimental group and blank group had no significant difference（P＞0.05）， Scl-90 of control group was significantly higher thanexperimental group and blank group （P＜0.05）. ②Cor and β-end had at 24h after injury had significant positive correlation with Scl-90 （r=0.166， P＜0.05；r=0.176， P＜0.05）. ConclusionShenmai injection used fo