咪唑安定联合异丙酚在电子胃肠镜检查术中临床应用.doc

咪唑安定联合异丙酚在电子胃肠镜检查术中临床应用[摘要] 目的：研究静脉麻醉咪唑安定和异丙酚联合应用于内镜检查中的可行性和安全性。方法：应用静脉麻醉胃肠镜检查226例作为观察组，常规胃肠镜检查238例作为对照组。胃肠镜检查均比较两组检查过程中的反应、操作时间及检查前后的心率、血压、血氧饱和度变化。结果：观察组所有患者无不适，愿意复检者217例（96%）；而对照组胃镜167例（93%）患者难受、肠镜58例（100%）患者难受，愿意复检者78例（33%）。观察组5~10 min内均完全清醒，均未遗留痛苦回忆。肠镜组镇静麻醉成功率观察组达回盲部48例（100%），对照组48例（83%）。观察组检查时间5～10 min完成，而对照组为8~30 min，两组比较，差异有统计学意义。两组均无严重不良反应。结论：无痛性内镜检查简便易行安全，麻醉状态下胃肠镜检查术可消除患者的紧张、恐惧情绪，操作顺利，效果满意，值得推广应用。 [关键词] 静脉麻醉；咪唑安定；异丙酚；胃镜；肠镜 [中图分类号] R614.2+4 [文献标识码] C [文章编号] 1674-4721（2011）08（b）-085-03 The clinical application of midazolam plus propofol for gastrointestinal endoscopy LI Shuguang1, ZHANG Long2, RUAN Guoyong1, LIANG Aixia1, QIU Guimei1 1.Department of Internal Medicine, the People’s Hospital of Xinxing County, Guangdong Province, Xinxing 527400, China; 2.Departmemt of Digestion, the First People’s Hospital of Guangzhou City, Guangdong Province, Guangzhou 510180, China [Abstract] Objective: To investigate the efficacy and safety of midazolam plus propofol for gastrointestinal endoscopy. Methods: The 226 patients as observation group were received intravenous anesthesia gastrointestinal endoscopy, and 238 patients as control group were received conventional gastrointestinal endoscopy. consciousness response, manipulation time, cardiac rate, blood pressure (BP), oxygen saturation of blood of the teo groups were observered during the study. Results: Patients in observation group were all well, wanted to rechecking 217 cases (96%); In control group, 167 (93%) patients unwell in enteroscope and 58 (100%) patients unwell in gastroscope. Patients in observation group were all cold sober in 5-10 minutes. 48 cases (100%) of enteroscope reached to ileocecus in observation group and 48 cases (83%) in control group. The review time of observation group was 5-10 minutes and control group was 8-30 minutes, there was difference between the two groups. Conclusion: Intravenous anesthesia during gastrointestinal endoscopy can eliminate patients’ fear mood and im