复元胶囊对气虚血瘀证患者临床疗效评价.doc

复元胶囊对气虚血瘀证患者临床疗效评价[摘要] 目的：探讨复元胶囊对气虚血瘀证患者症状、血液流变学及心功能的影响。方法：54例气虚血瘀证患者分为治疗组和对照组各27例，对照组应用西药常规治疗，治疗组在常规治疗基础上加用复元胶囊治疗，每次5粒，每日3次，疗程1个月。分别观察两组治疗前后症状、血液流变学及心功能指标。结果：治疗组在治疗后症状、血液流变学及心功能指标均较对照组有显著改善(P＜0.05或P＜0.01)。结论：复元胶囊对气虚血瘀证患者症状、血液流变学及心功能有显著改善。 [关键词] 复元胶囊；气虚；血瘀；血液流变学；心功能 [中图分类号] R969.4[文献标识码]B [文章编号]1673-7210（2008）04（c）-051-03 Evaluate the clinical curative effect of Fuyuan capsule in patients with qi deficiency and blood stasis HU Wen-xing，LI Rong-heng (Department of Integration of Traditional and Western Medicine, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016,China) [Abstract] Objective:To explore the influence of Fuyuan capsule treatment in patients with qi deficiency and blood stasis. Methods:54 cases with qi deficiency and blood stasis were divided into two groups，the Fuyuan capsule group and the control group，besidesbasic diseases were treated in two groups, the patients in Fuyuan capsule group were treated with Fuyuan capsules. Scores of symptom and indexes of hemorheology and heart function were tested after a month．The data were compared with that of pre-therapy.Results:The scores of symptoms were significantly lower than those of the control group(P＜0.05 or P＜0.01), the indexes of hemorheology were improved significantly than those of control group(P＜0.05 or P＜0.01), and the indexes of heart function were significantly higher than those of control group(P＜0.05 or P＜0.01)．Conclusion:Fuyuan capsule treatment can lessen symptoms, reduce blood viscosity，and enhance heart function of patients with qi deficiency and blood stasis [Key words] Fuyuan capsule; Qi deficiency; Blood stasis; Hemorheology; Heart function 老年人常伴气虚，气为血帅，血为气母，气行则血行，气滞则血瘀，因此气虚血瘀为老年病的常见病因，常见于冠心病、肺心病、糖尿病等老年病。其预后很差，给家庭和社会带来巨大的经济负担。因此，积极防治气虚血瘀，提高患者生活质量，降低死亡率已成为国际老年病领域急需解决的难题。复元胶囊是以益气、活血、补肾药组成的中药制剂。本试验就其对气虚血瘀证患者临床症状、血液流变学、心功能的影响进行研究，为该药的临床应用提供依据。 1资料与方法 1.1试验对象及分组 54例均为我院门诊及住院患者，均符合《中药新药临床研究指导原则》2005年版制定的气虚证症状分级量化标准及血瘀证症状分级量化标准，气虚证积分值≥7分