制剂技术与设备1（Preparation technology and equipment 1）.docVIP

制剂技术与设备1（Preparation technology and equipment 1） * preparation technology and equipment Equipment parameters: refers to the technical parameters or performance parameters of the equipment, generally including production capacity, volume, equipment specification, power supply, working temperature, power, package size, weight, etc. Meaning: it is the normal operation of equipment to ensure drug quality and safety in production of indicators, is the production process parameters and the basis of enterprise energy monitoring and surveillance, is the basis of equipment maintenance, maintenance and overhaul, is the basis of selection, configuration and installation equipment. GMP - drug production quality management specification Fluid: material in a liquid or gas state during production. Centrifugal pump: impeller, pump shell, pump shaft Gas binding: the centrifugal pump can not absorb the liquid when it is opened The fluid conveying equipment is divided into: centrifugal pump, reciprocating pump, rotary pump, vortex pump. Principle of centrifugal pump: before opening the pump, fill the pump shell with the transported liquid and the suction catheter. Open pump, pump shaft to drive the impeller centrifugal force generated by high speed rotation to liquid high speed to the periphery and into the pump shell, slows down, inside the volute channel after energy conversion can liquid has great static pressure, finally by higher pressure from the outlet to exclude catheter eduction and continue to be, at the same time because of the liquid has been left to the center of the high-speed rotating impeller outer part creates a low pressure area, inhalation of liquid surface pressure of liquid at the low pressure area form the pressure difference, causes the liquid by the bottom valve, suction catheter, suction into the pump. Centrifugal pump cavitation and how to avoid: when liquid flows through the pump, is changing its velocity and pressure, pressure at the entrance of a centrifug