虎杖中游离羟醛蒽醌（Free aldol anthraquinone in Polygonum cuspidatum）.doc

虎杖中游离羟醛蒽醌（Free aldol anthraquinone in Polygonum cuspidatum） Extraction and separation method of anthraquinone from Polygonum cuspidatum Abstract: Polygonum cuspidatum has Qingrejiedu, wind and dampness, promoting blood circulation effect, for the treatment of hepatitis, hyperlipemia, burn, scald and other diseases. People use modern pharmacological experimental techniques to further discover that Polygonum cuspidatum also has the functions of anti platelet aggregation, anti leukocyte depletion and regulating Ca2+ channels. Pharmacological studies on the active constituents of Polygonum cuspidatum is a hot spot in the study of Chinese herbal medicine. In order to obtain the effective constituents of Polygonum cuspidatum, anthraquinone derivatives only remain in the traditional processes such as boiling and alcohol extraction. Different extraction solvents were selected and different extraction methods were optimized. By comparing the effects of infiltration percolation, maceration, reflux, Soxhlet and ultrasonic extraction method of Polygonum cuspidatum anthraquinone extracting speed, efficiency, comparative advantages and disadvantages of various extraction methods, the extraction rate of different time granularity, the extraction of different medicines. Key words: Polygonum cuspidatum, anthraquinone, extraction and separation (1) the principle of experiment: hydroxyl quinone compounds and two styrene components can be dissolved in ethanol, so ethanol can be used to extract them. Hydroxy anthraquinone ether soluble in weak polar solvents, the solubility of polydatin in ether is very small, use them for ether solubility difference of hydroxyanthraquinone separation and polydatin, then use the hydroxyanthraquinone structure of the different performance of different acid, separating them by PH gradient extraction method. (two) experimental instruments and reagents Instruments: 722 grating spectrophotometer, analytical balance, ZF-1 type three, ultraviolet analyzer, KQ-