II-发育中的细胞信号.pptVIP

Developmental Biology;A signal from one group of cells influences the development of an adjacent group of cells;Cell signaling in development;Signal proteins and signal transduction pathways ;Signal proteins and signal transduction pathways ;The fibroblast growth factors ; ;The schematic diagram of the induction of the mouse embryonic lens;FGF8 is the inductive signal for inducing lens formation in the developing chick eye (I) ; ;The FGFs function through RTK signal transduction pathway ;Differentiation of photoreceptors in the Drosophila compound eye ;Differentiation of photoreceptors in the Drosophila compound eye ;RTK pathway component encoding genes involved in the induction of Drosophila photoreceptors ;Signal proteins and signal transduction pathways ;The Hedgehog (Hh) family ;shh is expressed in the nervous system, gut and limb bud;The Hedgehog (Hh) signal transduction pathway ;The Hedgehog (Hh) signal transduction pathway ;Mice lacking Shh function display major limb abnormalities as well as cyclopia- a single eye in the center of the forehead ;Mice lacking Shh function display major limb abnormalities as well as cyclopia- a single eye in the center of the forehead ;Defects in cholesterol modification of Hh cause cyclopia in the lamb ;Signal proteins and signal transduction pathways ;The Wnt family ;Wnt proteins play multiple roles in the development of the urogenital sysytem ;The Wnt signal transduction pathway ;Constitutive activation of Wnt pathway promotes cell division and may cause tumor formation ;Signal proteins and signal transduction pathways ;The TGF beta superfamily ;;The TGF beta superfamily ;;TGF beta superfamily members activate the Smad pathway ;TGF beta superfamily members activate the Smad pathway ;Signal proteins and signal transduction pathways ;The Notch signal transduction pathway ;The Notch signaling pathway ;Interference with endogenous Delta activity results in overproduction of primary neurons during Xenopus embryogenesis ;Delta