公驼宝克对肾阳虚大鼠影响.pdfVIP

摘 要 本文探讨了公驼宝克对氢化可的松注射液所致肾阳虚大鼠的影响。采用氢化可的 松注射液肌肉注射14天建立大鼠肾阳虚模型后，以宝克作为受试物进行灌胃干预14 天。观察大鼠外观、称量造模前后体重变化、进食情况、脏器指数及睾丸病理组织学 变化。同时检测肾阳虚大鼠血清中睾酮（T ）、促甲状腺激素（TSH ）、血肌酐（Scr ）、 尿素氮（BUN ）、一氧化氮（NO ）、超氧化物歧化酶（SOD）的含量。结果显示宝克 对肾阳虚大鼠所表现的“耗竭”现象逐渐减轻，同时发现宝克具有增加体重和进食量， 提高脏器指数，升高T ，降低TSH、Scr和BUN含量，提高SOD和NO含量，减轻睾丸 病理改变的特性。实验表明宝克能明显改善肾阳虚大鼠的病症。 关键词：宝克；肾阳虚；双峰驼；氢化可的松 Study on the Influence of Male Camel Bokhi on the Rats of Kidney Yang Deficiency Abstract In this paper, the influence of male camel Bokhi on the rats of Kidney Yang Deficiency was studied. The rats model groups of Kidney Yang Deficiency were established by intramuscular injecting hydrocortisone for 14 days, and then the rats were treated by oral administration of Bokhi for 14 days. The appearance, the changes of weight gain, the food intake, organ index and histological changes of experimental rats were observed. Meanwhile, the content of testesterone (T), thyroid stimulating hormone(TSH), serum creatinine(Scr), blood urea nitrogen(BUN), nitric oxide(NO), superoxide dismutase(SOD) in rats serum were detected. The result showed that the “exhaustion” phenomenon of the rats caused by deficiency of Kidney Yang were gradually alleviated by Bokhi which also improved the weight, the diat, organ index, testesterone(T), superoxide dismutase(SOD) and nitric oxide(NO). The contents of thyroid stimulating hormone(TSH), serum creatinine(Scr), serum urea nitrogen(BUN) and histological changes were reduced. Through the experiment, it was demonstrated that Bokhi can improve the rats of Kidney Yang Deficiency. Key words：Bokhi ；Kidney Yang Deficiency