APACHEⅡ评分和降钙素原对肺部感染预后的预测作用.docVIP

APACHEⅡ评分和降钙素原对肺部感染预后的预测作用 梅春霞，刘 娟，徐 智，戢福云，吴国明 (400037重庆,第三军医大学新桥医院全军呼吸内科研究所，全军呼吸病研究重点实验室/kcms/detail/51.1095.R1113.007.html(2014-02-19) The predictive value of APACHE II score and procalcitonin on the prognosis of patients with pulmonary infection Mei Chunxia, Liu Juan, Xu Zhi, Ji Fuyun, Wu Guoming（Institute of Human Respiratory Disease, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China） [Abstract] Objective To investigate whether acute physiology and chronic health evaluation II APACHE II) score and plasma procalcitonin are valuable predictors on the prognosis in patients with pulmonary infection. Methods Patients (n = 78) with pulmonary infection in ICU from March 2012 to May 2013 were recruited from Xinqiao Hospital. The data including age, gender, APACHE II score, blood gas analysis, erythrocyte sedimentation, C-reactive protein, lactic acid, procalcitonin, mortality within 28 d, occurrence of ARDS, and so on were collected and analyzed using the receiver operating characteristic curve. Results Among the 78 patients with pulmonary infection, 19 were death cases and 33 were ARDS cases. The statistical analysis showed that as compared to the survival group, APACHE II score and procalcitonin level were significantly higher while the oxygenation index was lower in the death group [23.3±7.5 vs. 15.5±6.2 (P0.001), 18.6(1.5-25.0)ng/mL vs. 1.0(0.3-25.0)ng/mL (P=0.044), 189.7±89.4 vs. 238.0±91.7 (P=0.048), respectively]. Similarly, though both of APACHE II score and procalcitonin level were also significantly higher and the oxygenation index was significantly lower in those who developed ARDS than in those who did not [19.9±8.3 vs. 15.6±6.0 (P=0.013), 8.3(1.2-25.0)ng/mL vs. 0.7(0.2-21.8)ng/mL (P=0.016), 190.9±82.6 vs. 252.1±92.4 (P=0.003), respectively]. Additionally, the results revealed that APACHE II score or procalcitonin level could solely predicate the occurrence of ARDS (0.651 vs. 0.657, P=0.929) and mortality withi