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hcg-人绒毛膜促性腺激素(Hcg- human chorionic gonadotropin)
hcg-人绒毛膜促性腺激素(Hcg- human chorionic gonadotropin)
HCG
Catalog
1. name
2. introduction
3. function
4. introduction
5. changes in HCG values after pregnancy
6. general HCG value comparison
7. progesterone and HCG normal values
8. urine HCG test method:
Clinical application of 9. urinary HCG
Limitations of 10. urine HCG detection methods:
11. what is a blood HCG test?
12. how does the blood HCG test do?
Name
HCG
introduce
Human chorionic gonadotropin (hCG), a glycoprotein secreted by trophoblast cells of the placenta, consists of two subunits, a- and b-. HCG enters mother blood after fertilization and rapidly grows up to the eighth week of pregnancy, then slows down until eighteenth to 20 weeks, then remains stable. Generally, a complete hCG level, at least up to 2.5MoM, is associated with down syndrome. The actual level of intact hCG was only 1.3MoM in the maternal blood of DS patients and could not be clearly identified in DS patients.
Effect
The hCG related molecules used for DS examination were free b-hCG and high glucose hCG (H-hCG). H-hCG related molecular screening is very sensitive to Down syndrome and can be urine sampling. H-hCG concentration in maternal plasma of children with DS was higher than that in non infected women (9.9-fold).
Free b-hCG is now the only known marker that can be used for both phase I and phase two screening. The average maternal free b-hCG level of DS syndrome was 1.9MoM, and that of healthy mother blood was 1.0MoM. HCG related molecular levels were also associated with fetal sex, and hCG levels were significantly higher in female infants than in male infants.
brief introduction
1) but the alpha subunit is common to the anterior pituitary hormones.
2) beta subunit is specific to HCG.
The complete HCG is produced by the trophoblast of the placental chorion.
Normal reference value:
(1) the normal value of blood HCG was 10 mu g/L,
(2) the normal value of beta -HCG is 3.1 mu g/L;
Changes in HCG values after pregnancy
HCG enters mother blood
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