I期非小细胞肺癌淋巴结微转移与预后关系的Meta分析.PDFVIP

维普资讯 《癌症》ChineseJournalofCancer。2004，23(2)：185—188 185 临床研 究 I期非小细胞肺癌淋巴结微转移与 预后关系的Meta分析 郑 智， 潘铁成， 李 军， 陈 涛， 宋定伟 ， 易 星 Meta-AnalysisofRelationshipbetweenLymphNode Micrometastasis andPrognosisinStage INon-SmallCellLungCancerPatients Zheng Zhi，PanTie—Cheng，LiJun，ChenTao，Song Ding—Wei，YiJun A【BSTRACT】BACKGROUND OBJECTIVE：Lymphnodemetastasisisan importantfactorforprognosisofnon—smallcelllungcancer (NSCLC)．There weredifferentopinionsaboutwhateffectdoeslymph nodemicrometastasishave on prognosis．This study was designed to collectliteratures oflymph node micrometastasisandprognosisinstage INSCLC patients，inordertoinvestigate D theirrelationship METHODS：The resultsfrOm eightliteratureson Iymph node micrometastasisandprognosisfrOm 1980to2002wereanalyzed syntheticallyby D meta—analysis The cumulative caseswere 536 NSCLC patientswith stage I disease RESULTS：Thedetection rateoflymph nodemicrometastasisranged C frOm 3．4％ to28．9％ ．and the rateofpositivecasesranged frOm 20％ to70％ ． The3一，5-yearover—survivalrateforpositivelymphnodemicrometastasispatients wasworse than those ofnegative lymph node micrometastasis patients：odd