北京市体重正常及超重肥胖儿童血糖血脂状况研究.doc

北京市体重正常及超重肥胖儿童血糖血脂状况研究【摘要】 目的 探讨超重、肥胖儿童血糖、血脂水平变化特点，为儿童肥胖的干预研究提供依据。方法 选择北京市3所中学、2所小学，根据2005-2006年中小学生体检身高、体重结果进行筛选，对自愿参加的1 045名7～15岁学生进行身高、体重测量。采集空腹肘静脉血测定血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和空腹血糖(FPG)。结果 FPG，TG，HDL-C，LDL-C在不同体型男、女儿童间差异均有统计学意义(P值均超重组正常组。男童TC异常检出率差异无统计学意义，FPG，TG，LDL-C偏高和HDL-C偏低的检出率均为肥胖组超重组正常组；女童FPG，TC，LDL-C异常检出率差异均无统计学意义(P值均0.05)，TG偏高和HDL-C偏低的检出率为肥胖组超重组正常组。结论 超重和肥胖儿童较体重正常儿童存在明显的血糖和血脂异常。应加强超重和肥胖儿童血糖和血脂检测，并进行综合干预。 【关键词】 体重；超重；肥胖症；血糖；血脂异常；儿童 【中图分类号】 R 179 R 589.2 【文献标识码】 A 【文章编号】 1000-9817(2007)12-1087-03 Fasting Glucose and Serum Lipids Level of Nomal-weight，Overweight and Obese Children in Beijing/ZHANG Shi-wei?*，MA Jun，WU Sheng-xin，et al. ?* Institute for Children and Adolescent Health，Peking University，Beijing(100083)，China 【Abstract】 Objective To explore the characteristics of fasting glucose and serum lipids in overweight and obese children，and to provide evidence for the intervention against children’s obesity. Methods The normal-weight，overweight and obese children were selected from three middle schools and two primary schools in Beijing according to the results of height and weight in students’ physical examination in 2005-2006. Height，weight，TC，TG，HDL-C，LDL-C and FPG were measured for all the 1 045 students aged 7-15 years old. Results There were significant differences in the levels of FPG，TG，HDL-C and LDL-C between boys and girls with different body types(Poverweightnormal weight. Except for TC，the prevalence of higher FPG，TG，LDL-C and lower HDL-C in male children was obesityoverweightnormal weight. There were no significant differences in abnormal prevalence of FPG，TC，LDL-C in female children(P0.05)，the prevalence of higher TG and lower HDL-C was obesityoverweightnormal-weight. Conclusion Compared with normal-weight children，overweight and obese children have abnormal fasting glucose and serum lipids，test of fasting glucose and serum lipids and comprehensive interventions for overweight and obese children should