大鼠局灶性脑缺血后星形胶质细胞过度增殖对局部微循环的影响.PDF

17 6 Vo l17N o6 200 8 12 CHINESE JOURNAL OFHISTOCHEMISTRY ANDCYTOCHEMISTRY Dec200 8 张 强 喻志源 田代实 陈 晨 唐颖馨 渠文生 徐沙贝 王 伟* ( , 4 30030) , , A L ZET 02% DM SO , r oscov t ne, , 7d FIT C , ( g l al f br llary ac d c pr ote n, G FA P) ; GF AP , , ro scov t ne ; ; Ro sco v t ne R7433 1 A DO I: 103870/ zg zzhx. 2008. 06 . 011 EFFECT OFASTROCYTICPROLIFERATION ON FOCAL MICROCIRCULATION AFTER MCAO IN RATS * Zhang Q ang, Yu Zh yuan, T an Da sh , Chen Chen, Tang Y ngx n, Qu Wensheng, Xu Shabe , Wang We (Department of Neurology, Tongj iH osp ital, Tongj iMedical College, H uazhong University of Science and Technology, uhan 430030, China) Abstract Object ve T o o bser ve t he ef fect of excess v e ast rocyt c prol f erat on on f ocal m croc rcu- l at on n h ppocampus and schem a boundary zone aft er m ddle cerebral art ery occlu s on ( MCA O ) M et ho ds Rat s w ere random ly d v ded nt o t he sham- operat ed g roup, schem a group and ro scov t ne gro upCer ebral schem a w as nduced by occlud ng the m ddle cer ebral art ery f or 1h n t he schem a and roscov t ne- tr eat ed g roups02% DM SO w as nf used nt o t he lat er al ventr cle by A L ZET m cro- o smo t c pump n t he schem a g roupT he ro scov t