features of “all lna” duplexes showing a new type of nucleic acid geometry特性的u201c放大器u201d工器显示一种新的核酸几何学.pdfVIP
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features of “all lna” duplexes showing a new type of nucleic acid geometry特性的u201c放大器u201d工器显示一种新的核酸几何学
Hindawi Publishing Corporation
Journal of Nucleic Acids
Volume 2012, Article ID 156035, 8 pages
doi:10.1155/2012/156035
Research Article
Features of “All LNA” Duplexes Showing a New Type of
Nucleic Acid Geometry
¨ 1, 2 ´ 1, 3 ¨ 4 4
Charlotte Forster, Andre Eichert, Dominik Oberthur, Christian Betzel,
2 5 ¨ 1
Reinhard Geßner, Andreas Nitsche, and Jens P. Furste
1 Institut fur Chemie und Biochemie, Freie Universitat Berlin, 14195 Berlin, Germany
¨ ¨
2 Chirurgische klinik II—Visceral, Transplantations-, Thorax- und Gefaßchirurgie, Universitatsklinik Leipzig, Liebigstraße 20,
¨ ¨
04103 Leipzig, Germany
3 Laboratory of Cell Biology and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York,
NY 10065, USA
4 Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology,
University of Hamburg, c/o DESY, 22603 Hamburg, Germany
5 Zentrum fur Biologische Sicherheit 1, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
¨
¨
Correspondence should be addressed to Jens P. Furste, fuerste@zedat.fu-berlin.de
Received 13 January 2012; Accepted 1 March 2012
Academic Editor: Subhendu Sekhar Bag
¨
Copyright © 2012 Charlotte Forster et al. This is an open access a
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