blood vessel density in basal cell carcinomas and benign trichogenic tumors as a marker for differential diagnosis in dermatopathology血管密度在基底细胞癌和良性trichogenic肿瘤在皮肤病理学作为鉴别诊断的标记.pdfVIP

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blood vessel density in basal cell carcinomas and benign trichogenic tumors as a marker for differential diagnosis in dermatopathology血管密度在基底细胞癌和良性trichogenic肿瘤在皮肤病理学作为鉴别诊断的标记.pdf

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blood vessel density in basal cell carcinomas and benign trichogenic tumors as a marker for differential diagnosis in dermatopathology血管密度在基底细胞癌和良性trichogenic肿瘤在皮肤病理学作为鉴别诊断的标记

Hindawi Publishing Corporation Journal of Skin Cancer Volume 2011, Article ID 241382, 5 pages doi:10.1155/2011/241382 Research Article Blood Vessel Density in Basal Cell Carcinomas and Benign Trichogenic Tumors as a Marker for Differential Diagnosis in Dermatopathology ¨ Julia Winter, Hermann Kneitz, and Eva-B. Brocker Department of Dermatology, University Hospital Wurzburg, Josef-Schneider-Strarße 2, 97080 Wurzburg, Germany ¨ ¨ ¨ Correspondence should be addressed to Eva-B. Brocker, broecker e@klinik.uni-wuerzburg.de Received 23 June 2010; Revised 27 August 2010; Accepted 15 September 2010 Academic Editor: Silvia Moretti Copyright © 2011 Julia Winter et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In order to get insight into the density of blood vessels in the stroma of benign and malignant trichogenic neoplasms, immunohistological quantiﬁcation of CD 31 positive vessels was performed in 112 tumors, comprised of 50 BCCs of nodular (35) or morphoeic (15) growth patterns, 17 Pinkus’ tumors, as well as 17 trichoepitheliomas of which 6 were desmoplastic, 8 trichofolliculomas, and 20 trichoblastomas. Methods. Vessel density was counted within the tumors, in the tumor-surrounding stroma, and, as a control, in the normal skin of the operation specimen. The results were compared using statistical methods. Results. Whereas, irrespective of the patients’ age and location