原创力文档bayesian and hierarchical bayesian analysis of response - time data with concomitant variables贝叶斯和分层贝叶斯分析的响应-时间数据与伴随的变量.pdfVIP
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bayesian and hierarchical bayesian analysis of response - time data with concomitant variables贝叶斯和分层贝叶斯分析的响应-时间数据与伴随的变量
J. Biomedical Science and Engineering, 2010, 3, 711-718 JBiSE
doi:10.4236/jbise.2010.37095 Published Online July 2010 (http://www.SciRP.org/journal/jbise/).
Bayesian and hierarchical Bayesian analysis of response - time
data with concomitant variables
Dinesh Kumar
Department of Community Medicine, Government Medical College, Chandigarh, India.
Email: dinesh_walia@
Received 9 January 2010; 19 January 2010; 30 January 2010.
ABSTRACT than one concomitant variables available for their ef-
fects to be adjusted. The exponential survival model
This paper considers the Bayes and hierarchical
Bayes approaches for analyzing clinical data on re- f y | λ λe-λy 0 ; λ0 , (1)
sponse times with available values for one or more
concomitant variables. Response times are assumed representing the death density function (DDF) corre-
to follow simple exponential distributions, with a dif- sponding to the survival time Y is assumed. We also as-
ferent parameter for each patient. The analyses are sume that the hazard λ for a patient under clinical inves-
carried out in case of progressive censoring assuming tigation is linearly related to measurements on ‘p’ con-
squared error loss function and gamma distribution comitant variables x , x , . . . , x as follows
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