beta-lactam antibiotic resistance among enterobacter spp. isolated from infection in animalsbeta-lactam抗生素耐药性感染动物的肠杆菌spp。孤立.pdfVIP

Advances in Microbiology, 2012, 2, 129-137 /10.4236/aim.2012.22018 Published Online June 2012 (http://www.SciRP.org/journal/aim) Beta-Lactam Antibiotic Resistance among Enterobacter spp. Isolated from Infection in Animals 1* 1* 1,2 3 1,2# Melissa S. Wilberger , Kate E. Anthony , Sasha Rose , Matt McClain , Luiz E. Bermudez 1Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, USA 2Department of Microbiology, College of Science, Oregon State University, Corvallis, USA 3Information Technology, College of Veterinary Medicine, Oregon State University, Corvallis, USA Email: #Luiz.Bermudez@ Received December 31, 2011; revised February 21, 2012; accepted March 7, 2012 ABSTRACT Nosocomial infections are frequent complications of hospitalization, caused by opportunistic pathogens that gain access to hosts undergoing invasive procedures, such as surgery, intubation, and placement of deep vein lines. Nosocomial infections in animal hospitals can infect other animals, as well as be transmitted to human personnel. Enterobacter is a genus of common gram-negative bacteria, which can be associated with antibiotic resistant hospital infections. Because of an outbreak in antibiotic resistance in the genus, we decided to investigate five years of Enterobacter infections in the Large Animal Services of the Lois Bates Acheson Veterinary Teaching Hospital (LBAVTH) at Oregon State Uni- versity. The demographics from 37 Enterobacter-infected patients of the LBAVTH were obtained from charts and ana- lyzed. The identified clusters of infections suggested possible patient-environment sources of i