competition between plasmid-bearing and plasmid-free organisms in a chemostat with pulsed input and washout在恒化器带质粒和不带质粒微生物之间的竞争与脉冲输入和冲刷.pdfVIP

Hindawi Publishing Corporation Mathematical Problems in Engineering Volume 2009, Article ID 204632, 17 pages doi:10.1155/2009/204632 Research Article Competition between Plasmid-Bearing and Plasmid-Free Organisms in a Chemostat with Pulsed Input and Washout Sanling Yuan,1 Yu Zhao,1 and Anfeng Xiao2 1 College of Science, Shanghai University for Science and Technology, Shanghai 200093, China 2 College of Bioengineering, Jimei University, Xiamen 361021, China Correspondence should be addressed to Sanling Yuan, sanling@ Received 5 June 2009; Accepted 11 September 2009 Recommended by Bin Liu We consider a model of competition between plasmid-bearing and plasmid-free organisms in the chemostat with pulsed input and washout. We investigate the subsystem with nutrient and plasmid-free organism and study the stability of the boundary periodic solutions, which are the boundary periodic solutions of the system. The stability analysis of the boundary periodic solution yields the invasion threshold of the plasmid-bearing organism. By using the standard techniques of bifurcation theory, we prove that above this threshold there are periodic oscillations in substrate, plasmid-free, and plasmid-bearing organisms. Numerical simulations are carried out to illustrate our results. Copyright q 2009 Sanling Yuan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1. Introduction The chemostat, a laboratory apparatus used for the continuous culture of microorganisms, has played an important role in microbiology and population biology. It is the most simple idealization of a biological system where the parameters are measurable