combined effects of aerobic exercise and diet on lipids and lipoproteins in overweight and obese adults a meta-analysis有氧运动和饮食的脂质和脂蛋白超重和肥胖的成年人一个荟萃分析.pdfVIP

Hindawi Publishing Corporation Journal of Obesity Volume 2012, Article ID 985902, 16 pages doi:10.1155/2012/985902 Research Article Combined Effects of Aerobic Exercise and Diet on Lipids and Lipoproteins in Overweight and Obese Adults: A Meta-Analysis George A. Kelley,1 Kristi S. Kelley,1 Susan Roberts,2 and William Haskell3 1 Department of Community Medicine, School of Medicine, West Virginia University, P.O. Box 9190, Morgantown, WV 26506-9190, USA 2 Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111-1524, USA 3 Prevention Research Center, Stanford University, Palo Alto, CA 94305-2004, USA Correspondence should be addressed to George A. Kelley, gkelley@ Received 18 August 2011; Accepted 1 December 2011 Academic Editor: Eliot Brinton Copyright © 2012 George A. Kelley et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This study used the aggregate data meta-analytic approach to determine the combined effects of aerobic exercise and diet on lipids and lipoproteins in overweight and obese adults. Twelve studies representing 859 men and women (443 intervention, 416 control) were included. Using random-effects models, statistically significant, intervention minus control reductions were found for TC (−12.8 mg/dL, 95% CI, −19.9 to −5.7), TC : HDL-C (−0.5 mg/dL, 95% CI, −0.8 to −0.1), LDL-C (−6.8 mg/dL, 95% CI, −11.8 to −1.8), and TG (−13.1 mg/dL, 95% CI, −21.2 to −5.0) but not HDL-C (−0.4 mg/dL, 95% CI, −2.3 to 1.6). Results remained robust when adjusted for publication bias, deleting each study from the model once, and collapsing results for