ciliated hepatic foregut cyst 103 cases in the world literature纤毛肝前肠囊肿103例在世界文学.pdfVIP

Open Journal of Pathology, 2012, 2, 45-49 45 Published Online July 2012 (http://www.SciRP.org/journal/ojpathology) /10.4236/ojpathology.2012.23010 Ciliated Hepatic Foregut Cyst: 103 Cases in the World Literature 1 2 3 1 1,4* Chenwi Ambe , Luis Gonzalez-Cuyar , Saleem Farooqui , Nader Hanna , Steven C. Cunningham 1Departments of Surgery, University of Maryland Medical Center, Baltimore, USA; 2Departments of Pathology, University of Mary- land Medical Center, Baltimore, USA; 3Department of Radiology, Saint Agnes Hospital Center, Baltimore, USA; 4Department of Surgery, Saint Agnes Hospital Center, Baltimore, USA. * Email: Steven.Cunningham@ st th th Received March 31 , 2012; revised April 27 , 2012; accepted May 8 , 2012 ABSTRACT Ciliated hepatic foregut cysts (CHFC) are rare, typically benign, lesions whose incidence has been increasing recently. Despite this increase in incidence, they remain rare and several key characteristics remain poorly understood, including the range of presentation and the risk of malignant conversion. To better understand CHFC, an extensive review of the international literature was performed. Characteristics including size, location, contents, presenting symptoms, and risk of malignancy were analyzed. In addition, an illustrative case is presented to highlight a potential pitfall in diagnosis: Although the presentation is thought to be typically painless or vaguely painful, these lesions may also present with hemorrhage and sudden severe abdominal pain. Importantly, although malignant degeneration is uncommon, analysis revealed that malignancy is significantly associated with size, which was significantly l