changes in erythrocyte sedimentation rate, white blood cell count, liver enzymes, and magnesium after gastric bypass surgery红细胞沉降率的变化、白细胞计数、肝酶和胃旁路手术后镁.pdfVIP

Hindawi Publishing Corporation Journal of Obesity Volume 2011, Article ID 273105, 6 pages doi:10.1155/2011/273105 Clinical Study Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery ¨ Hans-Erik Johansson, Arvo Haenni, and Bjorn Zethelius Department of Public Health and Caring Sciences/Geriatrics, Uppsala University Hospital, 75185 Uppsala, Sweden Correspondence should be addressed to Hans-Erik Johansson, hans-erik.johansson@pubcare.uu.se Received 13 June 2011; Accepted 27 September 2011 Academic Editor: Michael M. Murr Copyright © 2011 Hans-Erik Johansson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg). We investigated alterations, if any, in ESR, WBC, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and Mg after RYGBP. Methods. 21 morbidly obese nondiabetic patients who underwent RYGBP surgery were evaluated preoperatively (baseline), then 1 year (1st followup) and 3.5 years (2nd followup) after RYGBP and compared to an untreated control group. Results. Body mass index, ESR, WBC, ALT, and GGT were all significantly reduced at 1 year in the RYGBP group (30%, 35%, 20%, 45%, and 57%, resp.) while Mg increased by 6%, compared to control group