complications of corneal collagen cross-linking角膜胶原交联的并发症.pdfVIP

Hindawi Publishing Corporation Journal of Ophthalmology Volume 2011, Article ID 869015, 5 pages doi:10.1155/2011/869015 Review Article Complications of Corneal Collagen Cross-Linking Shikha Dhawan, Kavita Rao, and Sundaram Natrajan Cornea and Anterior Segment, Aditya Jyot Eye Hospital, Mumbai 400031, India Correspondence should be addressed to Shikha Dhawan, shikha dreams@rediff Received 28 February 2011; Revised 17 October 2011; Accepted 20 October 2011 Academic Editor: Antonio Leccisotti Copyright © 2011 Shikha Dhawan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cross-linking of corneal collagen (CXL) is a promising approach for the treatment of keratoconus and secondary ectasia. Several long-term and short-term complications of CXL have been studied and documented. The possibility of a secondary infection after the procedure exists because the patient is subjected to epithelial debridement and the application of a soft contact lens. Formation of temporary corneal haze, permanent scars, endothelial damage, treatment failure, sterile infiltrates, and herpes reactivation are the other reported complications of this procedure. Cross-linking is a low-invasive procedure with low complication and failure rate but it may have direct or primary complications due to incorrect technique application or incorrect patient’s inclusion and indirect or secondary complications related to therapeutic soft contact lens, patient’s poor hygiene, and undiagnosed concomitant ocular surface diseases. 1. Introduction keratoconus [2]. The present pa