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controversies in the management of endometrial cancer 2012子宫内膜癌的管理2012年争议
Open Journal of Obstetrics and Gynecology, 2012, 2, 373-381 OJOG
/10.4236/ojog.2012.24077 Published Online November 2012 (http://www.SciRP.org/journal/ojog/)
Controversies in the management of endometrial
cancer 2012
Fuat Demirkiran
Division of Gynacologic Oncology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Email: fuatdemirkiran@
Received 4 August 2012; revised 2 September 2012; accepted 11 September 2012
ABSTRACT type is Type I EC (endometrioid adenocancer) which
consists of nearly 85% - 90% of EC. Second type is non-
Endometrial cancer (EC) is the most frequent cancer
endometrioid endometrial cancer (Type II) which ac-
of the female genital tract, especially in developed
count for about 10% of EC. The most common non-
countries and the seventh most common cause of
endometrioid histology is papillary serous (10%), fol-
death from cancer in women in Western Europe.
lowed by clear cell (2% to 4%), mucinous (0.6% to 5%),
Major prognostic factors related to endometrial can-
and squamous cell (0.1% to 0.5%) [2]. Features of the
cer are stage, grade, and depth of myometrial inva-
type I carcinomas include increased exposure to
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