defining prediabetes in polycystic ovarian syndrome定义前驱糖尿病多囊性卵巢综合征.pdfVIP

Open Journal of Obstetrics and Gynecology, 2011, 1, 36-41 OJOG doi:10.4236/ojog.2011.12008 Published Online June 2011 (http://www.SciRP.org/journal/ojog/). Defining prediabetes in polycystic ovarian syndrome Mark P. Trolice College of Medicine, University of Central Florida, Orlando, USA. Email: drt@ Received 21 April 2011; revised 25 May 2011; accepted 3 June 2011. ABSTRACT Medicine (ASRM) resulting in revised criteria for mak- ing the diagnosis of PCOS using two of the following Objective: The article will review the associations three features: 1) oligo- or anovulation (i.e. cycle inter- between Prediabetes (PD) and Polycystic Ovarian val 35 d or 8 cycles/yr); 2) clinical or biochemical Syndrome (PCOS) and present factors that decrease signs of hyperandrogenism (i.e., demonstrated by ele- the progression of PD into type 2 diabetes mellitus vated total or free testosterone, DHEAS, free androgen (T2DM).Metformin will also be examined for its role index [2] or signs of hirsutism or acne; 3) ultrasound in ovulation induction, pregnancy and ameliorating evidence of polycystic ovaries (12 or more follicles in the metabolic syndrome. Study Design: Medline each ovary (2 mm - 9 mm), and/or increased ovarian search. Methods of study: Keyword search: Predia- volume (10 mL)—all at the exclusion of other etiolo- betes (PD), Polycystic Ovarian Syndrome (PCOS), gies (hyperprolactin