原创力文档determination of camylofin dihydrochloride and nimesulide in pharmaceutical preparation by gas chromatographycamylofin盐酸盐和nimesulide测定气相色谱法在药物制剂.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
determination of camylofin dihydrochloride and nimesulide in pharmaceutical preparation by gas chromatographycamylofin盐酸盐和nimesulide测定气相色谱法在药物制剂
American Journal of Analytical Chemistry , 2011, 2, 944-952
doi:10.4236/ajac.2011.28110 Published Online December 2011 (http://www.SciRP.org/journal/ajac)
Determination of Camylofin Dihydrochloride and
Nimesulide in Pharmaceutical Preparation by Gas
Chromatography
1,2 1 2 2
Rajeev Kumar R. Singh , Manapragada V. Rathnam , Sangeeta J. Singh , Raju V. K. Vegesna
1
Department of Chemistry, B. N. Bandodkar College of Science, Thane, India
2 Versapharm Incorporated, Warminister, USA
E-mail : kumarrajeevs@
Received February 27, 2011; revised May 22, 2011; accepted June 1, 2011
Abstract
This research paper describes simple analytical method for determination of Camylofin dihydrochloride and
Nimesulide in tablet formulation by Gas chromatography method. Benzoic acid was used as internal standard.
Validation was carried out in compliance with the International Conference on Harmonization guidelines.
The method utilized GC (Agilent Technologies 6890 N Network GC system with FID detector), and RTX-5
capillary column (5% diphenyl-95% dimethyl polysiloxane), 30 m × 0.53 mm, 1.5 µm as stationary phase.
Helium was used as the carrier gas at a flow rate of 1.5 mL·min–1 . The proposed method was validated for
linearity, LOD, LOQ, accuracy, precision, ruggedness and solution stability. It can be conveniently adopted
for routine quality control analysis.
Keywords: Capillary Column, Gas Chromatography, Pharmaceutical Preparations, Camylofin
Dihydrochloride, Nimesulide
1. Introduction preparatio
您可能关注的文档
- deriving the kutta-joukowsky equation and some of its generalizations using momentum balances推导了库达儒科夫斯基使用动量平衡方程和它的一些归纳.pdf
- deriving software acquisition process from maturity models—an experience report派生软件收购过程从成熟度模型的经验报告.pdf
- derived categories and the analytic approach to general reciprocity laws. part i衍生类别和一般的分析方法对等的法律。.pdf
- derived categories and the analytic approach to general reciprocity laws—part ii衍生类别和一般的分析方法互惠laws-part ii.pdf
- dermatitis herpetiformis from the genetics to the development of skin lesions从遗传学疱疹样皮炎皮肤损伤的发展.pdf
- deriving weights of criteria from inconsistent fuzzy comparison matrices by using the nearest weighted interval approximation推导权重的标准不一致的模糊比较矩阵,利用最近的加权间隔近似.pdf
- derived categories and the analytic approach to general reciprocity laws part iii衍生类别和一般互惠法律第三部分的分析方法.pdf
- derivations of quasi -algebras派生准代数.pdf
- desalination and alternative water-shortage mitigation options in israel a comparative cost analysis海水淡化和替代缺水缓解选项在以色列比较成本分析.pdf
- design and analysis of a 24 vdc to 48 vdc bidirectional dc-dc converter specifically for a distributed energy application设计和分析的24伏直流电48 vdc双向直流-直流转换器专门为分布式能源的应用程序.pdf
- determination of bacterial viability by selective capture using surface-bound siderophores测定细菌生存能力通过选择性捕获使用表面束缚含铁细胞.pdf
- determination of bond index of birnin- gwari iron ore in nigeria债券指数测定birnin - gwari铁矿石在尼日利亚.pdf
- detection on resources consumption drag of urbanization in china在中国检测资源消费城市化拖.pdf
- determination of di-n-butyl phosphate in organic streams of fbtr mixed carbide fuel reprocessing solution by gas chromatographic technique测定磷酸二丁在有机碳化fbtr流混合燃料后处理通过气相色谱技术的解决方案.pdf
- determination of conductivity in a heat equation电导率测定热方程.pdf
- determination of complex-valued parametric model coefficients using artificial neural network technique测定复值参数模型系数利用人工神经网络技术.pdf
- determination of differential enthalpy and isotherm by adsorption calorimetry确定微分焓和等温线的吸附量热法.pdf
- determination of cobalt in food, environmental and water samples with preconcentration by dispersive liquid-liquid microextraction测定食品中钴、环境水样和预浓缩分散液-液微萃取.pdf
- determination of essential & toxic metal and its transversal pattern from soil to tea brew确定基本和有毒金属及其横向模式从土壤茶酿造.pdf
- determination of genotoxic pollution of some hospital wastewater with salmonella ames test一些医院的确定基因毒性污染废水与沙门氏菌艾姆斯测试.pdf
文档评论（0）