effect of the administration of psidium guava leaves on blood glucose, lipid profiles and sensitivity of the vascular mesenteric bed to phenylephrine in streptozotocin-induced diabetic rats管理效果psidium番石榴叶在血糖、血脂水平和敏感的血管糖尿病大鼠肠系膜床苯肾上腺素在体外实验.pdfVIP

Vol.2, No.1, 138-145 (2012) Journal of Diabetes Mellitus /10.4236/jdm.2012.21023 Effect of the administration of Psidium guava leaves on blood glucose, lipid profiles and sensitivity of the vascular mesenteric bed to Phenylephrine in streptozotocin-induced diabetic rats 1 2 3* 3 Abdol Hassan Mansoori Bahrani , Habib Zaheri , Nepton Soltani , Fatemeh Kharazmi , Mansoor Keshavarz4, Mohammad Kamalinajad5 1Department of Science, Minab, Islamic Azad University, Minab, Iran 2Department of Biology, Faculty of Science, Shahid Bahonar University, Kerman, Iran 3Department of Physiology, School of Medicine and Cardiovascular Research Center, Hormozgan University of Medical Sciences, * Bandar Abbas, Iran; Corresponding Author: neptun.soltani@, nsoltani@hums.ac.ir 4Department of Physiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran 5Department of Pharmacognosy, Faculty of Pharmacy, Shahid Bahashti University of Medical Sciences, Tehran, Iran Received 25 November 2011; revised 27 December 2011; accepted 10 January 2012 ABSTRACT 1. INTRODUCTION The leaf of Psidium guava is traditionally used in Diabetes mellitus is a type of metabolic disorder that is Asia to manage, control and treat diabetes. We characterized by hyperglycemia and alterations in car- designed this study to elucidate the effect of the bohydrate, fat and protein metabolisms associated with administration of oral doses of aqueous and absolute or relative deficiencies in insulin secretion and/ ethanol extract from Psidium guava leaves on