原创力文档effect of collagen and collagen peptides from bluefin tuna abdominal skin on cancer cells影响胶原蛋白和胶原蛋白肽的蓝鳍金枪鱼腹部皮肤癌症细胞.pdfVIP
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effect of collagen and collagen peptides from bluefin tuna abdominal skin on cancer cells影响胶原蛋白和胶原蛋白肽的蓝鳍金枪鱼腹部皮肤癌症细胞
Vol.3, No.3, 129-134 (2011) Health
doi:10.4236/health.2011.33024
Effect of collagen and collagen peptides from bluefin
tuna abdominal skin on cancer cells
Sung-Hee Han*, Yuki Uzawa, Tatsuya Moriyama, Yukio Kawamura
Department of Applied Biological Chemistry, Graduate School of Agriculture, Kinki University, Naka-Machi, Nara, Japan;
*Corresponding Author: ykawamur@nara.kindai.ac.jp
Received 27 December 2010; revised 17 February 17 2011; accepted 28 February 2011.
ABSTRACT mals such as cows or pigs; however, marine animals
have garnered increased attention as a backup collagen
In the present study, we investigated the effect
resource ever since the onset of bovine spongiform en-
of collagen and collagen peptides from bluefin
cephalopathy (BSE) in the cattle industry [3].
tuna abdominal skin on cancer cells. Collagens
These days, consumption of fish worldwide has in-
were extracted from bluefin tuna ( Thunnus ori-
creased, especially with the Japanese, who consume a
entails) abdominal, mackerel, and carp skin. The
wide range of fish species [4]. Particularly, bluefin tuna
calf and salmon collagen were used reagent
(Thunnus Orientails) is one of the most popular types of
grade as a standard samples. The main protein
ba
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