effectiveness of sub-maximal intermittent exercise on muscle glycogen depletion, pgc-1α and pdk-4 gene expression的有效性sub-maximal间歇运动对肌肉糖原耗竭,pgc-1αpdk-4基因表达.pdfVIP

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effectiveness of sub-maximal intermittent exercise on muscle glycogen depletion, pgc-1α and pdk-4 gene expression的有效性sub-maximal间歇运动对肌肉糖原耗竭,pgc-1αpdk-4基因表达.pdf

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effectiveness of sub-maximal intermittent exercise on muscle glycogen depletion, pgc-1α and pdk-4 gene expression的有效性sub-maximal间歇运动对肌肉糖原耗竭,pgc-1αpdk-4基因表达

Open Journal of Molecular and Integrative Physiology, 2012, 2, 119-126 OJMIP /10.4236/ojmip.2012.24017 Published Online November 2012 (http://www.SciRP.org/journal/ojmip/) Effectiveness of sub-maximal intermittent exercise on muscle glycogen depletion, PGC-1α and PDK-4 gene expression 1 2,3 3,4 3,4 3* Keisuke Shiose , Takuro Tobina , Yasuki Higaki , Akira Kiyonaga , Hiroaki Tanaka 1Graduate School of Sports and Health Science, Fukuoka University, Fukuoka, Japan 2Faculty of Nursing and Nutrition, University of Nagasaki, Nagasaki, Japan 3Fukuoka University Institute for Physical Activity, Fukuoka, Japan 4Faculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan * Email: htanaka@fukuoka-u.ac.jp Received 25 September 2012; revised 25 October 2012; accepted 7 November 2012 ABSTRACT Keywords: Intermittent Exercise; Muscle Glycogen; Peroxisome Proliferator-Activated Receptor-γ Several metabolic gene expressions are regulated in Coactivator-1α; Pyruvate Dehydrogenase Kinase-4 concert with muscle glycogen status. We hypothesized that intermittent exercise performed at high but sub-maximal intensities with long recovery periods 1. INTRODUCTION would induce a low glycogen state that would stimu- Exercise training-induced increase in mitochondrial func- late peroxisome proliferator-activated receptor-γ coa- tion and fat-oxidat