effect of maternal exposure to octylphenol (4-tert-octylphenol) on the growth of the adrenal gland in male albino rats影响产妇接触octylphenol(4-tert-octylphenol)的增长在男性白化大鼠肾上腺.pdfVIP
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effect of maternal exposure to octylphenol (4-tert-octylphenol) on the growth of the adrenal gland in male albino rats影响产妇接触octylphenol(4-tert-octylphenol)的增长在男性白化大鼠肾上腺
Advances in Biological Chemistry, 2012, 2, 51-57 ABC
/10.4236/abc.2012.21006 Published Online February 2012 (http://www.SciRP.org/journal/abc/)
Effect of maternal exposure to octylphenol
(4-tert-octylphenol) on the growth of the adrenal
gland in male albino rats
Nafisa Mohamed Batarfi
Faculty of Science for Girls, King Abdulaziz University, Jeddah, Saudi Arabia
Email: Sala201018@
Received 21 September 2011; revised 5 November 2011; accepted 16 November 2011
ABSTRACT many chemicals such as detergents, paints, plastics, her-
bicides, and pesticides, and have become a major com-
4-tert-octylphenol (OP) is environmental pollutants
ponent in wastewater systems [1,2]. Because of large
that have been shown widespread impact estrogenic
quantities of alkylphenols are manufactured every year to
and toxic to the cells of mammals in culture. The ef-
provide substrate for the production of APEOs, they con-
fects of OP on the reproductive system of adult male
tinue to contaminate the environment along with their
vertebrates especially humans are virtually unknown.
respective alkylphenols. OP shows marked similarities to
Thus, in the present investigation, pregnant females
that of natural estrogens [2,3] and
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