alstonine as an antipsychotic effects on brain amines and metabolic changes鸡骨常山碱作为一种抗精神病药物对大脑胺和代谢变化的影响.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 418597, 7 pages doi:10.1093/ecam/nep002 Original Article Alstonine as an Antipsychotic: Effects on Brain Amines and Metabolic Changes 1, 2 1 1, 2 1 ˆ Viviane M. Linck, Ana P. Herrmann, Angelo L. Piato, Bernardo C. Detanico, ´ 1 ´ 3 4, 5 4, 5 Micheli Figueiro, Jorge Florio, Maurice M. Iwu, Christopher O. Okunji, Mirna B. Leal,1 and Elaine Elisabetsky1, 2 1 Laborat´orio de Etnofamacologia, ICBS, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite 500/202, 90050-170 Porto Alegre, RS, Brazil 2 Programa de P´os-Graduac¸˜ao em Ciˆencias Farmacˆeuticas, UFRGS, Porto Alegre, Brazil. Av. Ipiranga, 2752, 1◦ andar, 90610-000 Porto Alegre, RS, Brazil 3 Departamento de Patologia, Faculdade de Medicina Veterin´aria e Zootecnia, Universidade de S˜ao Paulo, USP, S˜ao Paulo-SP 05508-900, Brazil 4 International Centre for Ethnomedicine and Drug Development, University of Nigeria, Nsukka, Nigeria 5 Bioresources Development and Conservation Programme, University of Nigeria, Nsukka, Nigeria Correspondence should be addressed to Viviane M. Linck, vivilinck@ Received 4 August 2008; Accepted 12 January 2009 Copyright © 2011 Viviane M. Linck et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution,