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antimicrobial activities of essential oil and methanol extract of teucrium montanum精油和甲醇提取物的抗菌活动teucrium montanum.pdf

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antimicrobial activities of essential oil and methanol extract of teucrium montanum精油和甲醇提取物的抗菌活动teucrium montanum

eCAM 2007;4(S1)17–20 doi:10.1093/ecam/nem108 Original Article Antimicrobial Activities of Essential Oil and Methanol Extract of Teucrium montanum Nenad Vukovic, Tanja Milosevic, Slobodan Sukdolak and Slavica Solujic Department of Chemistry, Faculty of Science, University of Kragujevac, PO Box 12, Serbia This study was designed to examine the chemical composition of essential oil and the in vitro antimicrobial activities of essential oil and methanol extract of Teucrium montanum. The inhibitory effects of essential oil and methanol extracts of T. montanum were tested against 13 bacterial and three fungal species by using disc-diffusion method. GC/MS analyses revealed that essential oil contains mainly d-cadinene (17.19%), b-selinene (8.16%) a-calacorene (4.97%), 1,6-dimethyl-4-(1-methylethyl)-naphthalene (4.91%), caryophyllene (4.35%), copaene (4.23%), torreyol (3.91%), 4-terpineol (3.90%), cadina-1,4-diene (3.39%), b-sesquiphellandrene (3.34%), -cadinol (3.12%) and g-curcumene (3.18%). The essential oil has antibacterial as well as antifungal effect. Keywords: antimicrobial activity – essential oil – Teucrium montanum Introduction encountered with the long-term use of synthetic anti-