cancer, fertility preservation, and future pregnancy a comprehensive review癌症、生育保护和未来怀孕全面审查.pdfVIP

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cancer, fertility preservation, and future pregnancy a comprehensive review癌症、生育保护和未来怀孕全面审查.pdf

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cancer, fertility preservation, and future pregnancy a comprehensive review癌症、生育保护和未来怀孕全面审查

Hindawi Publishing Corporation Obstetrics and Gynecology International Volume 2012, Article ID 953937, 11 pages doi:10.1155/2012/953937 Review Article Cancer, Fertility Preservation, and Future Pregnancy: A Comprehensive Review Michelle L. Matthews,1 Bradley S. Hurst,1 Paul B. Marshburn,1 Rebecca S. Usadi,1 Margaret A. Papadakis,1 and Terry Sarantou2 1 Department of Obstetrics and Gynecology, Carolinas Medical Center, P.O. Box 32861, Charlotte, NC 28232, USA 2 Blumenthal Cancer Center, Carolinas Medical Center, 1025 Morehead Medical Drive, Charlotte, NC 28204, USA Correspondence should be addressed to Michelle L. Matthews, michelle.matthews@ Received 13 September 2011; Accepted 5 December 2011 Academic Editor: Einat Shalom-Paz Copyright © 2012 Michelle L. Matthews et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Given the increases in 5-year cancer survival and recent advances in fertility preserving technologies, an increasing number of women with cancer are presenting for discussion of fertility preserving options. This review will summarize the risk of infertility secondary to cancer treatment, available treatment options for fertility preservation, and techniques to reduce future risks for patients. Concerns that will be addressed include the risk of the medications and procedures, the potential delay in cancer treatment, likelihood of pregnancy complications, as well as the impact of future pregnancy on the recurrence risk of cancer. Recent advances in oocyte cryopreservation and ovarian stimulation protocols will be discussed. Healthcare providers need