serum levels of soluble p-selectin are increased and associated with disease activity in patients with beh?ets syndrome血清可溶性p-selectin水平增加,与患者的疾病活动本·等症.pdf
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serum levels of soluble p-selectin are increased and associated with disease activity in patients with beh?ets syndrome血清可溶性p-selectin水平增加,与患者的疾病活动本·等症
Mediators of Inflammation • 2005:4 (2005) 237–241 • PII: S0962935105506033 • DOI: 10.1155/MI.2005.237
SHORT COMMUNICATION
Serum Levels of Soluble P-Selectin Are Increased
and Associated With Disease Activity in Patients
With Behc¸et’s Syndrome
1 2 ¨ 2 3
Yusuf Turkoz, Cem Evereklioglu, Abdullah Ozkiris¸, Selc¸uk Mistik,
4 ¨ 5 6 ¨ ¨ 2
Murat Borlu, Ibrahim H. Ozerol, Fuat Duygulu, and Ozgur Ilhan
1 Department of Biochemistry, Inonu University Medical Faculty, Turkey
¨ ¨
2Department of Ophthalmology, Erciyes University Medical Faculty, Turkey
3Department of Family Medicine, Erciyes University Medical Faculty, Turkey
4Department of Dermatology, Erciyes University Medical Faculty, Turkey
5Department of Microbiology, Inonu University Medical Faculty, Turkey
¨ ¨
6Department of Orthopaedics and Traumatology, Erciyes University Medical Faculty, Turkey
Received 22 February 2005; accepted 18 April 2005
Behc¸et’s syndrome (BS) is a relapsing, chronic, inflammatory disease characterized by endothelial dysfunction, atherothromboem-
bogenesis, and leukocytoclastic vasculitis with complex immunologic molecular interactions. Generalized derangements of the lym-
phocyte and neutrophil populations, activated monocytes, and increased PM
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