short communication in vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against taenia solium cysts短通信吡喹酮的体外有效性测试,伊维菌素,对有钩绦虫oxfendazole囊肿.pdfVIP

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short communication in vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against taenia solium cysts短通信吡喹酮的体外有效性测试,伊维菌素,对有钩绦虫oxfendazole囊肿.pdf

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short communication in vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against taenia solium cysts短通信吡喹酮的体外有效性测试,伊维菌素,对有钩绦虫oxfendazole囊肿

Hindawi Publishing Corporation Journal of Parasitology Research Volume 2012, Article ID 363276, 4 pages doi:10.1155/2012/363276 Research Article Short Communication: In Vitro Efﬁcacy Testing of Praziquantel, Ivermectin, and Oxfendazole against Taenia Solium Cysts S. Cederberg,1 C. S. Sikasunge,2 ˚ 1 and M. V. Johansen3 A. Andersson, 1 Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark 2 Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, Lusaka, Zambia 3 DBL-Centre for Health Research and Development, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 57, 1870 Frederiksberg C, Denmark Correspondence should be addressed to M. V. Johansen, mvj@life.ku.dk Received 23 January 2011; Accepted 1 April 2011 Academic Editor: Boyko B. Georgiev Copyright © 2012 S. Cederberg et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Oxfendazole is recommended as the drug of choice for treating porcine cysticercosis. The drug does not kill brain cysts and is not registered for use in pigs. Latest its safety in the recommended dose has been questioned. The aim of this study was to investigate two alternative anthelminthics. The eﬃcacy of praziquantel and ivermectin was compared to oxfendazole In Vitro on Taenia solium. Cysts of T. solium were isolated from infected pork and incubated in culture media together with