sterile endophthalmitis after intravitreal injections无菌注射intravitreal后眼内炎.pdf

Hindawi Publishing Corporation Mediators of Inflammation Volume 2012, Article ID 928123, 6 pages doi:10.1155/2012/928123 Review Article Sterile Endophthalmitis after Intravitreal Injections ´ 1 2 ´ 1, 3 Joaquın Marticorena, Vito Romano, and Francisco Gomez-Ulla 1 Retina and Vitreous Unit, Instituto Oftlamologico Gomez-Ulla, 15705 Santiago de Compostela, Spain ´ ´ 2 Department of Ophthalmology, Second University of Naples, 81100 Naples, Italy 3 Department of Ophthalmology, University Hospital Complex of Santiago de Compostela, 15706 Santiago de Compostela, Spain ´ Correspondence should be addressed to Joaquın Marticorena, jmarticorena@ Received 1 July 2012; Accepted 7 August 2012 Academic Editor: Mario R. Romano ´ Copyright © 2012 Joaquın Marticorena et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Sterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration. The aetiology of sterile endophthalmitis, independently of the administered drug, remains uncertain and a multifactorial origin cannot be discarded. Sterile inflammation secondary both to intravitreal triamcinolone acetonide and to intravitreal bevacizumab share many characteristics such