a comparison of clinical and epidemiological characteristics of fatal human infections with h5n1 and human influenza viruses in thailand, 2004–2006临床和流行病学特点的比较致命的人类感染h5n1型禽流感和人类流感病毒在泰国,2004 - 2006.pdfVIP

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a comparison of clinical and epidemiological characteristics of fatal human infections with h5n1 and human influenza viruses in thailand, 2004–2006临床和流行病学特点的比较致命的人类感染h5n1型禽流感和人类流感病毒在泰国,2004 - 2006.pdf

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a comparison of clinical and epidemiological characteristics of fatal human infections with h5n1 and human influenza viruses in thailand, 2004–2006临床和流行病学特点的比较致命的人类感染h5n1型禽流感和人类流感病毒在泰国,2004 - 2006

A Comparison of Clinical and Epidemiological Characteristics of Fatal Human Infections with H5N1 and Human Influenza Viruses in Thailand, 2004–2006 1,2 3 1 3 Vivek Shinde *, Wanna Hanshaoworakul , James M. Simmerman , Ubolrat Narueponjirakul , Wiwan 4 4 3 3 1 Sanasuttipun , Suchada Kaewchana , Darin Areechokechai , Kumnuan Ungchusak , Alicia M. Fry 1 Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America, 2 Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America, 3 Bureau of Epidemiology, Thailand Ministry of Public Health, Nonthaburi, Thailand, 4 International Emerging Infections Program, Thailand Ministry of Public Health – United States Centers for Disease Control and Prevention Collaboration, Ministry of Public Health, Nonthaburi, Thailand Abstract Background: The National Avian Influenza Surveillance (NAIS) system detected human H5N1 cases in Thailand from 2004– 2006. Using NAIS data, we identified risk factors for death among H5N1 cases and described differences between H5N1 and human (seasonal) influenza cases. Methods and Findings: NAIS identified 11,641 suspect H5N1 cases (e.g. persons with fever and respiratory symptoms or pneumonia, and exposure to sick or dead poultry). All suspect H5N1 cases were tested with polymerase chain reaction (PCR) assays for influenza A(H5N1) and human influenza viruses. NAIS detected 25 H5N1 and 2074 human influenza cases; 17 (68%) and 22 (1%) were fatal, respectively. We collected detailed information from medical records on all H5N1 cases, all fatal human