硒对后肠微生物酵解作用和结肠癌的影响.PDF

3 4 生命科学研究 Vol. 3 No. 4 　 19 9 9 年12 月 Life Science Research Dec. 1999 : 1007-7847( 1999) 04-0292-07 X 邢 廷 铣 ( , 41012 ) : 给供试动物日粮添补较大剂量的硒( Se) , 既能影响 体内( 如血浆) Se 的含量, 也能 影响结肠微生物群落的酵解活性. 由于日粮中Se 的含量变化, 需Se 的结肠微生物对低Se 或 高 的反应特性不同. 随着添补量的增加, 产生 丁酸的能力也明显增加, 这说明日粮中的 Se Se 能影响后肠某些元素的释放、结肠微生物群落的组成及其酵解作用, 使之有利于动物的结肠 健康. 所以, Se 对结肠肿瘤有 一定的防治作用. : 硒; 后肠微生物; 结肠癌 : 938. 1 ; 73 . 3 　　　: Q R A Effects of Selenium on the Fermentation of Microflora and Colorectal Cancer XING T ing-xian ( , , Changsha Institute of Agricultural Modernization Chinese Academy of Sciences 41012 , , ) Changsha Hunan China : ( Abstract While maximal Se w as supplemented to the diet of experimental animal Sprague Daw ley) , diet Se can affect both the Se status of host as well as affecting the fermentative activity of CM C ( Colonic M icrobial Community ) . T he latter reflects a differential response of the Se-reguiring members of the CM C to low/ high Se exposure w hich, in this , . - case w as effected by altering the Se content of the diet The butyrate producing capacity can be increased as the increase of Se-supplementation. T his response may indicate that dietary Se to the extent that if affects the hind gu