腹腔镜子宫肌瘤切除术中垂体后叶素应用分析.doc

腹腔镜子宫肌瘤切除术中垂体后叶素应用分析[摘要] 目的:评价垂体后叶素在腹腔镜子宫肌瘤剔除术中的止血作用。方法:将行腹腔镜子宫肌瘤切除术的102例患者随机分为三组:Ⅰ组35例,腹腔镜术中应用垂体后叶素;Ⅱ组35例,腹腔镜术中应用催产素;Ⅲ组32例,不用任何药物。观察三组术中出血量及手术时间。结果:术中出血量:Ⅰ组(65±35) ml比Ⅱ组(120±55) ml、Ⅲ组(140±65) ml少,比较有显著性差异(P0.05)。手术时间:Ⅰ组(61±25) min比Ⅱ组(88±27) min、Ⅲ组(95±24) min短,有显著性差异(P0.05)。结论:在腹腔镜子宫肌瘤切除术中应用垂体后叶素止血作用明显,便于手术操作。 [关键词] 腹腔镜;垂体后叶素;止血;子宫肌瘤 [中图分类号] R711.74[文献标识码]A [文章编号]1673-7210(2010)04(c)-050-02 Application of hypophysin on myomectomy under lapaorscopic LU Huiling, HAN Linxiao, LIU Yanyan, LU Huixian, FENG Shaoting (Department of Obstetrics and Gynecology, Shilong People’s Hospital of Dongguan City, Dongguan523326, China) [Abstract] Objective: To evaluate the hemostatic effect of hypophysin in laparoscopic myomectomy. Methods: 102 cases of patients with laparoscopic myomectomy were divided into three groups: group Ⅰ(under laparoscope hypophysin Injection of 35 cases on parts of uterine fibroids), group Ⅱ(under laparoscope Oxytocin Injection site of uterine fibroids, 35 cases); group Ⅲ of 32 cases without any drugs. 3 groups were observed blood loss and operation time. Results: Blood loss: group Ⅰ (65±35) ml was less than that in group Ⅱ (120±55) ml and group Ⅲ (140±65) ml, there was a significant difference (P0.05). Operative time: group Ⅰ(61±25) min shorter than that in group Ⅱ(88±27) min and group Ⅲ (95±24) min, there was a significant difference (P0.05). Conclusion: Laparoscopic myomectomy by using hypophysin on hemostatic effect is application obvious, more easier on surgical operation. [Key words] Laparoscope; hypophysin; Hemostasis; Uterine fibroids 随着人们生活水平及意识的提高,微创手术越来越受到人们的关注,现在很多医院均已开展了腹腔镜手术。既往子宫肌瘤采取开腹手术,近年来腹腔镜下子宫肌瘤切除术因创伤小、恢复快而被广泛应用于临床工作中。但腹腔镜子宫肌瘤切除术手术难度较开腹手术大,尤其术中止血困难,更有甚者因术中出血多、止血困难而改开腹手术。既往的经验是术中应用20 U催产素给予肌瘤部位注入,以减少术中出血,但是在临床工作中发现术中应用催产素作用有限,术中子宫创面的出血仍较多。近年来我科试验性应用肌瘤部注入垂体后叶素12 U,其止血效果较好。本文回顾性分析102例腹腔镜下子宫肌瘤切除术中应用垂体后叶素或催产素进行止血的效果比较。现报道如下: 1 资料与方法 1.1 一般资料 选择2006年1月～2008年5月在我院要求行腹腔镜下子宫肌瘤剔除术的患者102例,按入院时间随机分为三组,Ⅰ组为应用垂体后叶素组35例,Ⅱ组为