bothrops jararaca peptide with anti-hypertensive action normalizes endothelium dysfunction involved in physiopathology of preeclampsia具窍蝮蛇属jararaca肽降压行动使内皮功能紊乱参与子痫前期的生理病理学规范化.pdfVIP

Bothrops jararaca Peptide with Anti-Hypertensive Action Normalizes Endothelium Dysfunction Involved in Physiopathology of Preeclampsia 1,2 1,2 3 1,2 Gabriel Benedetti , Katia L. P. Morais , Juliano R. Guerreiro , Eduardo Fontana de Oliveira , Mara 4 5 5 6 7 7 Sandra Hoshida , Leandro Oliveira , Nelson Sass , Ivo Lebrun , Henning Ulrich , Claudiana Lameu *, Antonio Carlos Martins de Camargo1,8 ´ 1 Center for Applied Toxinology-Centros de Pesquisa, Inovacio e Difusao, Instituto Butantan, Sao Paulo, Brazil, 2 Departamento de Bioquımica, Universidade Federal de ˜ ´ ´ ´ ´ ˆ ´ Sao Paulo, Sao Paulo, Brazil, 3 Laboratorio de Bioquımica de Proteınas, Centro de Biotecnologia Agrıcola, Departamento de Ciencias Biologicas, Escola Superior de ´ ´ ˜ Agricultura ‘‘Luiz de Queiroz’’, University of Sao Paulo, Sao Paulo, Brazil, 4 Laboratorio de Fisiologia Obstetrica, Faculdade de Medicina, Universidade de Sao Paulo, Sao ´ ´ ´ Paulo, Brazil, 5 Hospital Maternidade Vila Nova Cachoeirinha, Sao Paulo, Brazil, 6