changing domesticity of aedes aegypti in northern peninsular malaysia reproductive consequences and potential epidemiological implications改变家庭生活在马来西亚半岛北部的埃及伊蚊生殖后果和潜在的流行病学意义.pdfVIP

Changing Domesticity of Aedes aegypti in Northern Peninsular Malaysia: Reproductive Consequences and Potential Epidemiological Implications 1 1 1 1 2 Rahman G. M. Saifur *, Hamady Dieng , Ahmad Abu Hassan , Md Rawi Che Salmah , Tomomitsu Satho , Fumio Miake2, Ahmad Hamdan1 1 School of Biological Sciences, Universiti Sains Malaysia, Penang, Malaysia, 2 Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan Abstract Background: The domestic dengue vector Aedes aegypti mosquitoes breed in indoor containers. However, in northern peninsular Malaysia, they show equal preference for breeding in both indoor and outdoor habitats. To evaluate the epidemiological implications of this peridomestic adaptation, we examined whether Ae. aegypti exhibits decreased survival, gonotrophic activity, and fecundity due to lack of host availability and the changing breeding behavior. Methodology/Principal Findings: This yearlong field surveillance identified Ae. aegypti breeding in outdoor containers on an enormous scale. Through a sequence of experiments incorporating outdoors and indoors adapting as well as adapted populations, we observed that indoors provided better environment for the survival of Ae. aegypti and the observed death patterns could be explained on the basis of a difference in body size. The duration of gonotrophic period was much shorter in large-bodied females. Fecundity tended to be greater in indoor acclimated females. We also found increased tendency to multiple feeding in outdoors adapted females, which were smaller in size compared to their outdoors breeding counterparts. Conclusion/Significance: The data presented here suggest that ac