原创力文档children with severe malnutrition can those at highest risk of death be identified with the who protocol患有严重营养不良的儿童死亡的那些风险最高可以确定的协议.pdfVIP
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children with severe malnutrition can those at highest risk of death be identified with the who protocol患有严重营养不良的儿童死亡的那些风险最高可以确定的协议
PLoS MEDICINE
Children with Severe Malnutrition: Can Those
at Highest Risk of Death Be Identified
with the WHO Protocol?
1,2,3* 1,4 1 1 1,5
Kathryn Maitland , James A. Berkley , Mohammed Shebbe , Norbert Peshu , Michael English ,
Charles R. J. C. Newton1,6
1 Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, Kilifi, Kenya, 2 Department of Paediatrics, Faculty of Medicine, Imperial College,
London, United Kingdom, 3 Wellcome Trust Centre for Clinical Tropical Medicine, Imperial College, London, United Kingdom, 4 Centre for Clinical Vaccinology and Tropical
Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom, 5 Department of Paediatrics, John Radcliffe Hospital, University of Oxford, Oxford, United
Kingdom, 6 Neurosciences Unit, Institute of Child Health, The Wolfson Centre, Mecklenburgh Square, London, United Kingdom
Funding: The study was supported A B S T R A C T
by the Kenya Medical Research
Institute (KEMRI) and The Wellcome
Trust. The funders had no role in
study design, data collection and Background
analysis, decision to publish, or
preparation of the manuscript. With strict adherence to international recommended treatment guidelines, the case fatality
for severe malnutrition ought to be less than 5%. In African hospitals, fatality rates of 20% are
Competing Interests: The authors common and are often attributed to poor training and faulty case management. Improving
have declared that no competing
interests exist.
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