原创力文档cellular and molecular effect of mehp involving lxrα in human fetal testis and ovary细胞和分子的影响mehp lxrα参与人类胎儿睾丸和卵巢.pdfVIP
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cellular and molecular effect of mehp involving lxrα in human fetal testis and ovary细胞和分子的影响mehp lxrα参与人类胎儿睾丸和卵巢
Cellular and Molecular Effect of MEHP Involving LXRa in
Human Fetal Testis and Ovary
1,2,3 1,2,3 ´ 1,2,3 1,2,3
Vincent Muczynski , Charlotte Lecureuil , Sebastien Messiaen , Marie-Justine Guerquin ,
1,2,3 1,2,3 1,2,3 4 4
Thierry N’Tumba-Byn , Delphine Moison , Wassim Hodroj , Hinde Benjelloun , Jan Baijer ,
1,2,3 ´ 5 5 ´ 1,2,3 1,2,3
Gabriel Livera , Rene Frydman , Alexandra Benachi , Rene Habert , Virginie Rouiller-Fabre *
´
1 University Paris Diderot, Sorbonne Paris Cite, Laboratory of Development of the Gonads, Unit of Stem Cells and Radiation, Fontenay-aux-Roses, France, 2 CEA, DSV,
´
iRCM, SCSR, LDG, 92265 Fontenay-aux-Roses, France, 3 INSERM, Unite 967, F-92265, Fontenay aux Roses, France, 4 Flow Cytometry Facility, CEA – DSV/iRCM/SCSR, F-92265
´ ´ ˆ ´ ` ´
Fontenay aux Roses, France, 5 Service de Gynecologie-Obstetrique, Hopital A. Beclere,- Universite Paris Sud, F-92141 Clamart, France
Abstract
Background: Phthalates have been shown to have reprotoxic effects in rodents and human during fetal life. Previous
studies indicate that some members of th
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