distribution of major health risks findings from the global burden of disease study分布的主要健康风险从全球疾病负担研究发现.pdfVIP

Open access, freely available online PLoS MEDICINE Distribution of Major Health Risks: Findings from the Global Burden of Disease Study 1* 2 1 3 1 2 Anthony Rodgers , Majid Ezzati , Stephen Vander Hoorn , Alan D. Lopez , Ruey-Bin Lin , Christopher J. L. Murray , Comparative Risk Assessment Collaborating Group 1 Clinical Trials Research Unit, School of Population Health, University of Auckland, New Zealand, 2 Harvard School of Public Health, Boston, Massachusetts, United States of America, 3 School of Population Health, University of Queensland, Brisbane, Australia Competing Interests: The authors A B S T R A C T have declared that no competing interests exist. ADL is a member of the editorial board of PLoS Medicine . Background Author Contributions: AR, ME, Most analyses of risks to health focus on the total burden of their aggregate effects. The ADL and CJLM designed the study. distribution of risk-factor-attributable disease burden, for example by age or exposure level, can SVH and RBL analyzed the data. inform the selection and targeting of specific interventions and programs, and increase cost- AR, ME, SVH, and ADL contrib- uted to writing the paper. effectiveness. Academic Editor: Thomas Novotny, University of California Methods and Findings at San Francisco, United States of America For 26 selected risk factors, expert working groups conducted comprehensive reviews of data on risk-factor exposure and hazard for 14 epidemiological subregions of the world, by age Citation: Rodgers A, Ezzati M, Vander Ho