dna demethylation and usf regulate the meiosis-specific expression of the mouse miwidna脱甲基和普遍服务基金监管meiosis-specific鼠标miwi的表情.pdfVIP

DNA Demethylation and USF Regulate the Meiosis- Specific Expression of the Mouse Miwi Yu Hou, Jia Yuan, Xiang Zhou, Xiazhou Fu, Hanhua Cheng*, Rongjia Zhou* Department of Genetics, College of Life Sciences, Wuhan University, Wuhan, China Abstract Miwi, a member of the Argonaute family, is required for initiating spermiogenesis; however, the mechanisms that regulate the expression of the Miwi gene remain unknown. By mutation analysis and transgenic models, we identified a 303 bp proximal promoter region of the mouse Miwi gene, which controls specific