dopamine d1, d2, d3 receptors, vesicular monoamine transporter type-2 (vmat2) and dopamine transporter (dat) densities in aged human brain多巴胺d1、d2、d3受体,水泡单胺转运蛋白2型(vmat2)和多巴胺转运体(dat)密度在人类大脑年龄.pdfVIP

Dopamine D , D , D Receptors, Vesicular Monoamine 1 2 3 Transporter Type-2 (VMAT2) and Dopamine Transporter (DAT) Densities in Aged Human Brain 1¤ 1 2,3 1,2,4,5,6 1,7,8 Jianjun Sun , Jinbin Xu , Nigel J. Cairns , Joel S. Perlmutter , Robert H. Mach * 1 Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 2 Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 3 Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 4 Department of Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 5 Department of Occupational Therapy, Washington University School of Medicine, St. Louis, Missouri, United States of America, 6 Department of Physical Therapy, Washington University School of Medicine, St. Louis, Missouri, United States of America, 7 Department of Cell Biology amd Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 8 Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America Abstract The dopamine D , D , D receptors, vesicular monoamine transporter type-2 (VMAT2), and dopamine transporter (DAT) 1 2 3 densities were measured in 11 aged human brains (aged 77–107.8, mean: 91 years) by quantitative autoradiography. The density of D 3 3