drug use and receipt of highly active antiretroviral therapy among hiv-infected persons in two u.s. clinic cohorts吸毒和收据的高活性抗逆转录病毒疗法在感染艾滋病毒的人在两个美国诊所军团.pdfVIP

Drug Use and Receipt of Highly Active Antiretroviral Therapy among HIV-Infected Persons in Two U.S. Clinic Cohorts 1 2 2 1 Catherine C. McGowan *, David D. Weinstein , Charles P. Samenow , Samuel E. Stinnette , Gema 1 1 1,3 4 1,3 Barkanic , Peter F. Rebeiro , Timothy R. Sterling , Richard D. Moore , Todd Hulgan 1 Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, 2 Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, 3 Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, 4 Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America Abstract Objective: Drug use and receipt of highly active antiretroviral therapy (HAART) were assessed in HIV-infected persons from the Comprehensive Care Center (CCC; Nashville, TN) and Johns Hopkins University HIV Clinic (JHU; Baltimore, MD) between 1999 and 2005. Methods: Participants with and without injection drug use (IDU) history in the CCC and JHU cohorts were evaluated. Additional analysis of persons with history of IDU, non-injection drug use (NIDU), and no drug use from CCC were performed. Activity of IDU and NIDU also was assessed for the CCC cohort. HAART use and time on HAART were analyzed according to drug use category and site of care. Results: 1745 persons were included from CCC: 268 (15%) with IDU history and 796 (46%) with NIDU history.