no association between oxytocin receptor (oxtr) gene polymorphisms and experimentally elicited social preferences之间没有联系催产素受体(oxtr)基因多态性与实验引起社会偏好.pdfVIP

No Association between Oxytocin Receptor (OXTR) Gene Polymorphisms and Experimentally Elicited Social Preferences 1,2 3 4 5 6 Coren L. Apicella *, David Cesarini , Magnus Johannesson , Christopher T. Dawes , Paul Lichtenstein , ¨ 4 7 8 Bjorn Wallace , Jonathan Beauchamp , Lars Westberg 1 Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, United States of America, 2 Department of Human Evolutionary Biology, Harvard University, Boston, Massachusetts, United States of America, 3 Department of Economics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, 4 Department of Economics, Stockholm School of Economics, Stockholm, Sweden, 5 Department of Political Science, University of California San Diego, La Jolla, California, United States of America, 6 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, 7 Department of Economics, Harvard University, Boston, Massachusetts, United States of America, 8 Department of Pharmacology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden Abstract Background: Oxytocin (OXT) has been implicated in a suite of complex social behaviors including observed choices in economic laboratory experiments. However, actual studies of associations between oxytocin receptor (OXTR) gene variants and experimentally elicited social preferences are rare. Methodology/Principal Findings: We test hypotheses of associations between social preferences, as measured by behavior in two economic games, and 9 single nucleotide polymorphisms (SNPs) of the OXTR gene in a sample of Swedish twins (n = 684