nuclear grp75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma核grp75视黄酸受体结合促进神经元分化的神经母细胞瘤.pdfVIP

Nuclear GRP75 Binds Retinoic Acid Receptors to Promote Neuronal Differentiation of Neuroblastoma 1,2 2,3 4 3,5 6 Yu-Yin Shih , Hsinyu Lee , Akira Nakagawara , Hseuh-Fen Juan , Yung-Ming Jeng , Yeou-Guang 7 8,9 10 2,3 9,11 1 Tsay , Dong-Tsamn Lin , Fon-Jou Hsieh , Chien-Yuan Pan *, Wen-Ming Hsu *, Yung-Feng Liao * 1 Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, 2 Institutes of Zoology, National Taiwan University, Taipei, Taiwan, 3 Department of Life Science, National Taiwan University, Taipei, Taiwan, 4 Department of Molecular Biology and Oncology, Chiba Cancer Center Research Institute, Chiba University Graduate School of Medicine, Chiba, Japan, 5 Institute of Molecular and Cellular Biology, National Taiwan University, Taipei, Taiwan, 6 Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, 7 Institute of Biochemistry and Molecular Biology and Proteomics Research Center, National Yang-Ming University, Taipei, Taiwan, 8 Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, 9 Childhood Cancer Foundation, Taipei, Taiwan, 10 Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, 11 Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan Abstract Retinoic acid (RA) has been approved for th