solitary fibrous tumors and so-called hemangiopericytoma孤独的纤维性肿瘤和所谓的血管外皮细胞瘤.pdfVIP

Hindawi Publishing Corporation Sarcoma Volume 2012, Article ID 690251, 6 pages doi:10.1155/2012/690251 Review Article Solitary Fibrous Tumors and So-Called Hemangiopericytoma Nicolas Penel,1, 2 Eric Yaovi Amela,1 Gauthier Decanter,1 Yves-Marie Robin,3 and Perrine Marec-Berard4 1 General Oncology Department, Centre Oscar Lambret, 3 Rue F Combemale, 59020 Lille, France 2 Medical School (EA 2694)—Lille Nord de France University, 59000 Lille, France 3 Pathology Departement, Centre Oscar Lambret, 3 Rue F Combemale, 59020 Lille, France 4 Oncopediatric Departement, Centre Leon Berard, 28 Rue Laennec, 69008 Lyon, France ´ ´ Correspondence should be addressed to Nicolas Penel, n-penel@o-lambret.fr Received 12 January 2012; Accepted 31 January 2012 Academic Editor: Isabelle Ray-Coquard Copyright © 2012 Nicolas Penel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We have reviewed the literature data regarding the spectrum of tumors including solitary fibrous tumor and hemangiopericytoma with special focus on definition of the disease, discussion of the criteria for malignancy, and the key elements of standard treatment of localized disease. We have discussed the emerging concepts on the tumor biology and the different systemic treatments (chemotherapy and molecular-targeted therapies). 1. Introduction (Doege-Potter syndrome) [4, 6]. In the Magdeleinat series, osteoarthropathy and hypoglycemia occurred in 4