unilateral auditory neuropathy caused by cochlear nerve deficiency单方面的听觉神经病变引起的耳蜗神经缺陷.pdfVIP

Hindawi Publishing Corporation International Journal of Otolaryngology Volume 2012, Article ID 914986, 5 pages doi:10.1155/2012/914986 Clinical Study Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency Cheng Liu,1 Xingkuan Bu,1 Feiyun Wu,1, 2 and Guangqian Xing1, 3 1 WHO Collaborating Centre for the Prevention of Deafness and Hearing Impairment, Nanjing Medical University, Nanjing 210029, China 2 Department of Radiology, First Affi liated Hospital of Nanjing Medical University, Nanjing 210029, China 3 Department of Otolaryngology, First Affi liated Hospital of Nanjing Medical University, Nanjing 210029, China Correspondence should be addressed to Xingkuan Bu, bxkuan@ Received 19 July 2011; Revised 2 October 2011; Accepted 30 November 2011 Academic Editor: Robert K. Shepherd Copyright © 2012 Cheng Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To explore possible corelationship between the cochlear nerve deficiency (CND) and unilateral auditory neuropathy (AN). Methods. From a database of 85 patients with unilateral profound sensorineural hearing loss, eight who presented with evoked otoacoustic emissions (EOAEs) or cochlear microphonic (CM) in the affected ear were diagnosed with unilateral AN. Audiological and radiological records in eight patients with unilateral AN were retrospectively reviewed. Results. Eight cases were diagnosed as having unilateral AN caused by CND. Seven had type “A” tympanogram with normal EOAE in both ears. The other patient had unilateral type “B” tympanogram and absent OAE but CM recorded, consistent with middle ear effusion in the affected