血清同型半胱氨酸水平与颈动脉粥样硬化的关系探讨.PDFVIP

《海南医学》2012年第23卷第4期 Vol.23 No.4 February 2012 doi:10.3969/j.issn.1003-6350.2012.04.046 ·经验交流· 血清同型半胱氨酸水平与颈动脉粥样硬化的关系探讨 1 2 邵振兴 ，孙金凤 1 2 （靖江市中医院神经内科、B 超室 ，江苏 靖江 214500 ） 【摘要】 目的 探讨血清同型半胱氨酸水平（Hcy ）与颈动脉粥样硬化程度的关系。方法 选择住院治疗的 82 例缺血性脑卒中患者，经彩色多普勒B 超检查的结果分为颈动脉正常组、颈动脉内膜-中层增厚组、颈动脉粥 样硬化斑块组，并测定血清同型半胱氨酸水平，进行组间比较。结果 颈动脉粥样硬化斑块组的血清同型半 胱氨酸水平明显高于颈动脉正常组及颈动脉内膜-中层增厚（IMT ）组，差异有统计学意义(P0.05) ；颈动脉内 膜-中层增厚组与颈动脉正常组血清同型半胱氨酸水平比较，差异有统计学意义(P0.05) 。结论 血清同型半 胱氨酸水平高低与颈动脉粥样硬化程度呈正相关，血清同型半胱氨酸水平(Hcy)越高，颈动脉粥样硬化斑块、 狭窄越严重。 【关键词】 血清同型半胱氨酸水平；颈动脉内膜-中层增厚；颈动脉粥样硬化斑块 【中图分类号】 R54 【文献标识码】A 【文章编号】 1003—6350（2012 ）04—102—02 Relationshipofserumhomocysteineandcarotidatherosclerosis. SHAOZhen-xing,SUNJin-feng.Departmentof Neurology,TCMHospitalofJingjiang,Jingjiang214500,Jiangsu,CHINA 【Abstract】 Objective To study the relationship of serum homocysteine (Hcy) and carotid atherosclerosis. Methods 82 hospitalized cases with ischemic stroke by color Doppler ultrasound B, were divided into normal carot- id artery, carotid artery intima-media thickening group, carotid artery atherosclerosis group, and serum homocysteine levels were examined and compared among three groups. Results Serum level of homocysteine (Hcy) group in carot- id artery atherosclerosis group was significantly higher than that in the normal carotid artery and carotid artery intima- media thickening (IMT) group (P0.05 ); serum levels of homocysteine (Hcy) in carotid artery intima-media thicken- ing group was significantly higher than that in the normal carotid artery (P0.05). Conclusion Serum homocysteine le